Figure adapted from Wang et al. (2016)*. Differences in colorectal cancer (CRC) and endometrioid cancer (EC) nucleotide shifts observed in microsatellite instability (MSI) profiles.
- A. Alterations in repeat length for all loci in all MSI-high CRC (cases, n = 46) and EC (light blue, n = 20) are plotted in the graph.
- B. Alterations in repeat length for five individual mononucleotide markers are plotted in the graph.
- C. The distribution of mean absolute shifts in repeat lengths of five markers per tumor differs significantly between CRC (dark blue) and EC (light blue). The mean nucleotide shifts in EC (light blue) are significantly smaller than those of CRC (dark blue) in all markers. P < 0.0001.
Wang, Y. et al. (2016). Differences in Microsatellite Instability Profiles between Endometrioid and Colorectal Cancers. The Journal of Molecular Diagnostics 19, 57-64. https://doi.org/10.1016/j.jmoldx.2016.07.008