Articles

Explore a selection of recent articles our company and collaborators have generated. We will continue to be active contributors to the scientific community, further advancing the delivery of precision medicine and improved patient outcomes.

The opinions and conclusions expressed in the following publications are those of the individual authors and do not necessarily reflect the views and opinions of Biocartis and/or its employees.

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Evaluation of a Fully Automated Idylla Test System for Microsatellite Instability in Colorectal Cancer

Li et al. - Clin Colorectal Cancer. - May 2019

Evaluation of KRAS, NRAS and BRAF hotspots mutation detection for patients with metastatic colorectal cancer using direct DNA pipetting in a fully-automated platform and Next-Generation Sequencing for laboratory workflow optimization

Gilson et al. - PLoS One - July 2019

Impact of Pre-Analytical Factors on MSI Test Accuracy in Mucinous Colorectal Adenocarcinoma: A Multi-Assay Concordance Study.

Malapelle et al. - Cells - September 2020

Comparison of Two Rapid Assays for the Detection of BRAF V600 Mutations in Metastatic Melanoma including Positive Sentinel Lymph Nodes

Long-Mira et al. - Diagnostics (Basel) - March 2022

Integration of rapid PCR testing as an adjunct to NGS in diagnostic pathology services within the UK: evidence from a case series of non-squamous, non-small cell lung cancer (NSCLC) patients with follow-up

Finall et al. - J Clin Path. - January 2022

Large UK study shows rapid EGFR Testing with Idylla™ alongside NGS has potential to enhance lung cancer patient health outcomes. Average turnaround time to report EGFR mutations with the Idylla™ EGFR Mutation Test was 3.8 days, versus 17 days for reporting of NGS results. 6% of the patients died before the NGS report was available. Of the 17 patients whose condition deteriorated rapidly, 3 (18%) were identified as having an actionable variant in EGFR that could have been treated with tyrosine kinase inhibitors.

Evaluation of the Idylla EGFR Mutation Test on formalin-fixed, paraffin-embedded tissue of human lung cancer

Xu et al. - J Thorac Dis - January 2024